List of selected publications

Please see a full list of publications  here (Google Scholar).

Wagner SA, Satpathy S, Beli P, Choudhary C.
SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.
EMBO J. 2016 Sep 1;35(17):1868-84.
Wild T, Larsen SY, Narita T, Schou J, Nilsson J, Choudhary C.
The spindle assembly checkpoint is not essential for viability of human cells with genetically lowered APC/C activity.
Cell Reports. 2016 Mar 1;14(8):1829-40.
Schölz C, Lyon D, Refsgaard JC, Jensen LJ, Choudhary C, Weinert BT.
Avoiding abundance bias in the functional annotation of posttranslationally modified proteins.
Nat Methods. 2015 Oct 29;12(11):1003-4.
Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, Narita T, Sixma TK, Choudhary C, Bekker-Jensen S, Mailand N.
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
Nature. 2015 Nov 19;527(7578):389-93.
Weinert BT, Moustafa T, Iesmantavicius V, Zechner R, Choudhary C.
Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions.
EMBO J. 2015 Nov 3;34(21):2620-32.
Satpathy S, Wagner SA, Beli P, Gupta R, Kristiansen T, Malinova D, Francavilla C, Tolar P, Bishop GA, Hostager BS, Choudhary C.
Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.
Mol Syst Biol. 2015 Jun 2;11(6):810.
Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Jun QI, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, Choudhary C.
Unraveling lysine deacetylase inhibitor specificities for endogenous acetylation sites.
Nat Biotechnol. 2015 Apr;33(4):415-23.
Choudhary C, Weinert BT, Yoshida Y, Verdin E, Mann M.
The growing landscape of lysine acetylation links metabolism and cell signalling.
Nat Rev Mol Cell Biol. 2014 Jul 23;15(8):536-50.
Weinert BT, Iesmantavicius V, Moustafa T, Schölz C, Wagner SA, Magnes C, Zechner R, and Choudhary C.
Acetylation Dynamics and Stoichiometry in Saccharomyces cerevisiae.
Mol Syst Biol. 2014 Jan 30;10:716.
Weinert BT, Schölz C, Wagner SA, Iesmantavicius V, Su D, Daniel JA, Choudhary C.
Lysine succinylation is a frequently occurring posttranslational modification in prokaryotes and eukaryotes and extensively overlap with acetylation.
Cell Reports. 2013 Aug 29;4(4):842-51.
Weinert BT, Iesmantavicius V, Wagner SA, Gummesson B, Beli P, Nyström T, and Choudhary C.
Acetyl-Phosphate is a Critical Determinant of Lysine Acetylation in E. coli.
Mol Cell. 2013 Jul 25;51(2):265-72.
Povlsen LK, Beli P, Wagner SA, Sylvestersen KB, Poulsen SL, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
Systems-wide analysis of ubiquitylation dynamics reveals a key role of PAF15 ubiquitylation in DNA damage bypass.
Nat Cell Biol. 2012 Sep 23;14(10):1089-98.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85.
Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
Mol Cell. 2012 Apr 27;46(2):212-25.
Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles.
Mol Cell Proteomics. 2011 Oct;10(10):M111.013284.
Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen, LJ and Choudhary C.
Proteome-Wide Mapping of the Drosophila Acetylome Demonstrates a High Degree of Conservation of Lysine Acetylation.
Sci. Signaling. 4, ra48 (2011).
Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady N, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D and Dikic I.
Phosphorylation of the Autophagy Receptor Optineurin restricts Salmonella Growth.
Science. 2011 Jul 8;333(6039):228-33.
Kaidi A, Weinert BT, Choudhary C, Jackson SP.
Human SIRT6 promotes DNA end resection through CtIP deacetylation.
Science. 2010 Sep 10;329(5997):1348-53.
Choudhary C and Mann M.
Decoding signaling networks by mass spectrometry-based proteomics.
Nat Rev Mol Cell Biol. 2010 Jun;11(6):427-39.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther T, Olsen JV, Mann M.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science. 2009 Aug 14;325(5942):834-40.
Choudhary C, Olsen JV, Brandts C, Cox J, Böhmer FD, Gerke V, Schmidt-Arras D, Berdel WE, Müller-Tidow C, Mann M, Serve H.
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes.
Mol Cell. 2009 Oct 23;36(2):326-39.